Attack phase: one tablet in the morning and one tablet in the evening; maintenance phase: one tablet per day
Food Supplement useful in cases of neuro-inflammatory processes chronic pain associated with numerous pelvic area disorders.
One-Time Purchase:
€ 36,50
In stock
Attack phase: one tablet in the morning and one tablet in the evening; maintenance phase: one tablet per day
Keep out of reach of children under 3 years. Do not exceed the recommended daily dose. Food Supplements should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. In case of impaired liver function, biliary function or gallstones, use of the product is not recommended. Do not use during pregnancy and breastfeeding. Do not use for prolonged periods without consulting a doctor. If you are taking medication, you should seek medical advice. Store at room temperature in a cool, dry place. Avoid exposure to localised heat sources, sunlight and contact with water. The shelf life refers to the product correctly stored in unopened packaging. Do not disperse in the environment after use.
Engler D et a. Guidelines on Chronic Pelvic Pain, European Association of Urology, 2018; linee Guida SIU – Il Dolore Pelvico Cronico. Coordinatore: Sandro Sandri, con la collaborazione di Monica Sommariva. Revisori: Francesco Cappellano, Francesco Pesce, Paolo Politi; Winter J, Bevan S, Campbell EA. Capsaicin and pain mechanisms. Br J Anaesth. 1995 Aug;75(2):157-68; Turini D, Beneforti P, Spinelli M, Malagutti S, Lazzeri M. Heat/burning sensation induced by topical application of capsaicin on perineal cutaneous area: new approach in diagnosis and treatment of chronic prostatitis/chronic pelvic pain syndrome? Urology. 2006 May;67(5):910-3; De Petrocellis L, Davis JB, Di Marzo V. Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. FEBS Lett. 2001 Oct 12;506(3):253-6; Ambrosino P, Soldovieri MV, Russo C, Taglialatela M. Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide. Br J Pharmacol. 2013 Mar;168(6):1430-44; Hesselink JM. Evolution in pharmacologic thinking around the natural analgesic palmitoylethanolamide: from nonspecific resistance to PPAR-α agonist and effective nutraceutical. J Pain Res. 2013 Aug 8;6:625-34; Gabrielsson L, Mattsson S, Fowler CJ. Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy. Br J Clin Pharmacol. 2016 Oct;82(4):932-42.; Sun J, Chen F, Braun C, Zhou YQ, Rittner H, Tian YK, Cai XY, Ye DW. Role of curcumin in the management of pathological pain. Phytomedicine. 2018 Sep 15;48:129-140. ; Tasneem S, Liu B, Li B, Choudhary MI, Wang W. Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents. Pharmacol Res. 2019 Jan;139:126-140.; Ohishi T, Gotob S, Monirac P, Isemura M, Nakamura Y. Anti-inflammatory Action of Green Tea. Anti-Inflam & Anti-Allergy Agents in Med Chem, 2016, 15, 74-90 ; Bimonte S, Cascella M, Schiavone V, Mehrabi-Kermani F, Cuomo A. The roles of epigallocatechin-3-gallate in the treatment of neuropathic pain: an update on preclinical in vivo studies and future perspectives. Drug Des Devel Ther. 2017 Sep 13;11:2737-2742.; Ternesten-Hasséus E, Johansson EL, Millqvist E. Cough reduction using capsaicin. Respir Med. 2015 Jan;109(1):27-37.; European Food Safety Authority (EFSA), Parma, Italy. Refined exposure assessment for curcumin. EFSA Journal 2014;12(10):3876; Thomas R, Williams M, Sharma H, Chaudry A, Bellamy P. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer–the U.K. NCRN Pomi-T study. Prostate Cancer Prostatic Dis. 2014 Jun;17(2):180-6.
Aloe vera, camomile and calendula help to soothe while Pinus pinaster counteracts oxidation resulting in a natural skin defence. It is the ideal product as a recovery whenever soothing and calming is needed.
eco
friendly
vegan
made with
love
€ 39,50